(Q100152585)

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SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9672170)

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1 reference

8 July 2022

Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9672170

1 reference

8 July 2022

p21 RAS:GDP [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

p21 RAS:GTP [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

p-11Y PDGFR mutatnt receptors:GRB2:SOS1 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

PDGFRA activating mutations in gastrointestinal stromal tumors.

1 reference

8 July 2022

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib

1 reference

8 July 2022

Different inhibitory effect of imatinib on phosphorylation of mitogen-activated protein kinase and Akt and on proliferation in cells expressing different types of mutant platelet-derived growth factor receptor-alpha

1 reference

8 July 2022

PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations

1 reference

8 July 2022

Gastrointestinal stromal tumours: origin and molecular oncology.

1 reference

8 July 2022

The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q100152585)

SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors

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