(Q100152597)

English

GRB2:SOS1 complex binds to PDGFRA extracellular domain dimers

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9672158)

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Statements

biological process

1 reference

8 July 2022

Signaling by PDGFRA extracellular domain mutants

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9672158

1 reference

8 July 2022

GRB2-1:SOS1 [cytosol]

1

object has role

1 reference

8 July 2022

p-11Y PDGFRA extracellular domain dimers [endoplasmic reticulum membrane]

1

object has role

1 reference

8 July 2022

p-11Y PDGFRA extracellular domain dimers:GRB2:SOS1 [endoplasmic reticulum membrane]

1

object has role

1 reference

8 July 2022

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

1 reference

8 July 2022

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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