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FLT3LG dimer:FLT3 dimer autophosphorylates
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9604767)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
part of
FLT3 Signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
exact match
https://identifiers.org/reactome:R-HSA-9604767
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
has part(s)
ATP(4-)
quantity
12
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
FLT3LG dimer:FLT3 dimer [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
Active FLT3 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
ADP(3-)
quantity
12
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
FLT3LG dimer:FLT3 dimer [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
FLT3:FLT3-binding type II TKIs [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
cites work
Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
Oncogenic Flt3 receptors display different specificity and kinetics of autophosphorylation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
Identifiers
Reactome ID
R-HSA-9604767
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9604767
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