(Q100156084)

English

Active FLT3:GRB2 binds GAB2

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9606624)

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Statements

biological process

1 reference

8 July 2022

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9606624

1 reference

8 July 2022

Active FLT3: GRB2 [plasma membrane]

1

object has role

1 reference

8 July 2022

GRB2 associated binding protein 2

1

object has role

1 reference

8 July 2022

Active FLT3:GRB2:GAB2 [plasma membrane]

1

object has role

1 reference

8 July 2022

Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

1 reference

8 July 2022

A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival

1 reference

8 July 2022

Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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