(Q100162712)

English

Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9024326)

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Statements

biological process

1 reference

8 July 2022

NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9024326

1 reference

8 July 2022

ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm]

1

value of statement has role

1 reference

8 July 2022

NR1H3, NR1H2 ligands [nucleoplasm]

1

value of statement has role

1 reference

8 July 2022

ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm]

1

value of statement has role

1 reference

8 July 2022

GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus

1 reference

8 July 2022

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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