(Q100241123)

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Signaling by NOTCH4

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9013694)

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8 July 2022

Notch signaling pathway

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8 July 2022

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-9013694

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NOTCH4 Activation and Transmission of Signal to the Nucleus

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NOTCH4 Intracellular Domain Regulates Transcription

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8 July 2022

Negative regulation of NOTCH4 signaling

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8 July 2022

Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors

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8 July 2022

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

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8 July 2022

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

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8 July 2022

Notch signaling in primary endothelial cells

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8 July 2022

Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression

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8 July 2022

Notch4 reveals a novel mechanism regulating Notch signal transduction

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8 July 2022

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors

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8 July 2022

Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis

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8 July 2022

Active form Notch4 promotes the proliferation and differentiation of 3T3-L1 preadipocytes

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8 July 2022

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

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8 July 2022

The NOTCH4-HEY1 pathway induces epithelial mesenchymal transition in head and neck squamous cell carcinoma

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8 July 2022

Notch4 Signaling Induces a Mesenchymal-Epithelial-like Transition in Melanoma Cells to Suppress Malignant Behaviors

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8 July 2022

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

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8 July 2022

Notch4 promotes gastric cancer growth through activation of Wnt1/β-catenin signaling

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8 July 2022

Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways

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8 July 2022

Dengue virus up-regulates expression of notch ligands Dll1 and Dll4 through interferon-β signalling pathway

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8 July 2022

An Epstein-Barr virus protein interacts with Notch

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8 July 2022

Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function

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8 July 2022

Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling

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8 July 2022

Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh).

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8 July 2022

AKT and 14-3-3 regulate Notch4 nuclear localization.

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8 July 2022

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis

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8 July 2022

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8 July 2022

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

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8 July 2022

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

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8 July 2022

Kit and PDGFR-alpha activities are necessary for Notch4/Int3-induced tumorigenesis

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8 July 2022

The ANK repeats of Notch-4/Int3 activate NF-κB canonical pathway in the absence of Rbpj and causes mammary tumorigenesis

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8 July 2022

Identifiers

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8 July 2022

(Q100241123)

Signaling by NOTCH4

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