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Butirosin-biosynthetic Gene Cluster from Bacillus circulans.

scientific article published in March 2012

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Butirosin-biosynthetic Gene Cluster from Bacillus circulans. (English)

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http://api.crossref.org/works/10.7164%2Fantibiotics.53.1158

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YASUMASA OTA

1

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HIDEYUKI TAMEGAI

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2

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FUMITAKA KUDO

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3

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HISAKO KURIKI

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4

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AYUMI KOIKE-TAKESHITA

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5

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TADASHI EOUCHI

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6

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KATSUMI KAKINUMA

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7

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publication date

1 March 2012

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full work available at URL

https://www.jstage.jst.go.jp/article/antibiotics1968/53/10/53_10_1158/_pdf

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19 March 2024

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published in

The Journal of Antibiotics

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volume

53

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issue

10

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page(s)

1158-1167

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Molecular cloning of the gene for the key carbocycle-forming enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics and its comparison with dehydroquinate synthase.

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Purification and characterization of 2-deoxy-scyllo-inosose synthase derived from Bacillus circulans. A crucial carbocyclization enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics.

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Confirmation of in vitro synthesis of 2-deoxy-scyllo-inosose, the earliest intermediate in the biosynthesis of 2-deoxystreptamine, using cell free preparations of Streptomyces fradiae

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Substrate Specificity of 2-Deoxy-scyllo-inosose Synthase, the Starter Enzyme for 2-Deoxystreptamine Biosynthesis, toward Deoxyglucose-6-phosphates and Proposed Mechanism

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Biosynthesis of butirosin in Bacillus circulans NRRL B3312: identification by sequence analysis and insertional mutagenesis of the butB gene involved in antibiotic production

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Biosynthesis of butirosins. II. Biosynthetic pathway of butirosins elucidated from cosynthesis and feeding experiments

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10.7164/ANTIBIOTICS.53.1158

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(Q105326542)

Butirosin-biosynthetic Gene Cluster from Bacillus circulans.

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