(Q112999068)

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HTR1A binds HTR1A antagonists

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9648268)

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8 July 2022

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-9648268

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8 July 2022

5-hydroxytryptamine receptor 1A

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8 July 2022

HTR1A antagonists [extracellular region]

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8 July 2022

HTR1A:HTR1A Antagonist drugs [plasma membrane]

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8 July 2022

Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study

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8 July 2022

New insight into the therapeutic role of 5-HT1A receptors in central nervous system disorders

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8 July 2022

Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy

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8 July 2022

S 16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-Yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: I. Receptorial and neurochemical profile in compar

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8 July 2022

Interactions of (+)- and (-)-8- and 7-hydroxy-2-(di-n-propylamino)tetralin at human (h)D3, hD2 and h serotonin1A receptors and their modulation of the activity of serotoninergic and dopaminergic neurones in rats.

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8 July 2022

[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.

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8 July 2022

2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors

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8 July 2022

Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.

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8 July 2022

Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine1A receptor agonist

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8 July 2022

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

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8 July 2022

A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging

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8 July 2022

Pharmacological characterization of recombinant human 5-hydroxytryptamine1A receptors using a novel antagonist radioligand, [3H]WAY-100635.

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8 July 2022

Synthesis, receptor binding and functional studies of mesoridazine stereoisomers

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8 July 2022

High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells

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8 July 2022

The in vitro pharmacology of the beta-adrenergic receptor pet ligand (s)-fluorocarazolol reveals high affinity for cloned beta-adrenergic receptors and moderate affinity for the human 5-HT1A receptor

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8 July 2022

SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue

1 reference

8 July 2022

Discovery of the first potent, selective 5-hydroxytryptamine1D receptor antagonist.

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8 July 2022

Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist

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8 July 2022

The pharmacological characterization of a novel selective 5-hydroxytryptamine1A receptor antagonist, NAD-299.

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8 July 2022

Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders

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8 July 2022

N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-nitrophenyl) cyclohexanecarboxamide: a novel pre- and postsynaptic 5-hydroxytryptamine(1A) receptor antagonist active on the lower urinary tract

1 reference

8 July 2022

Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists

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8 July 2022

Affinity of cyamemazine, an anxiolytic antipsychotic drug, for human recombinant dopamine vs. serotonin receptor subtypes

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8 July 2022

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q112999068)

HTR1A binds HTR1A antagonists

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