(Q12746346)

http://www.ebi.ac.uk/interpro/protein/P41146

http://www.ebi.ac.uk/interpro/protein/A0A0G2JQE4

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

2 references

13 November 2019

17 September 2016

2 references

13 November 2019

20 March 2016

nociceptin receptor activity

English

molecular function

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

G protein-coupled receptor activity

4 references

24 April 2018

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

protein C-terminus binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

nociceptin receptor activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

G protein-coupled receptor activity

5 references

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

nociceptin receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0A0G2JQE4

integral component of membrane

cell component

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0A0G2JQE4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0A0G2JQE4

2 references

integral component of plasma membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

integral component of plasma membrane

3 references

8 April 2019

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

biological process

response to estradiol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

3 references

8 April 2019

Immunoglobulin G1 Fc fragment-tagged human opioid receptor-like receptor retains the ability to inhibit cAMP accumulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

8 April 2019

Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

1 reference

8 April 2019

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

positive regulation of urine volume

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

regulation of sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

negative regulation of blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

regulation of locomotor rhythm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

positive regulation of gastric acid secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

positive regulation of sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

sensory perception of pain

3 references

negative regulation of voltage-gated calcium channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

neuropeptide signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

chemical synaptic transmission

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41146&geneProductId=UniProtKB:P41146

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

negative regulation of cAMP-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

G protein-coupled opioid receptor signaling pathway

1 reference

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

IDA

1 reference

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

conditioned place preference

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41146

G protein-coupled opioid receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0A0G2JQE4

physically interacts with

1 reference

8866

17 August 2016

1 reference

1681

17 August 2016

1 reference

1684

17 August 2016

1 reference

1691

17 August 2016

1 reference

1692

17 August 2016

1 reference

1693

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2364605

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3304244

has part(s)

GPCR, rhodopsin-like, 7TM

2 references

http://www.ebi.ac.uk/interpro/protein/P41146

http://www.ebi.ac.uk/interpro/protein/A0A0G2JQE4

Identifiers

MeSH descriptor ID

D000094942

subject named as

Nociceptin Receptor

0 references

MeSH tree code

D12.776.543.750.695.620.887

0 references

D12.776.543.750.720.600.610.887

0 references

D12.776.543.750.750.555.610.887

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

20 March 2016

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference