(Q14821020)

English

Coagulation factor II

mammalian protein found in Mus musculus

thrombin
prothrombin
F2

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Gamma-carboxyglutamic acid-rich (GLA) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Peptidase S1, PA clan

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Thrombin light chain domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

prothrombin/thrombin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Kringle-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Kringle superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Kringle domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Gamma-carboxyglutamic acid-rich (GLA) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Kringle, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thrombin light chain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, serine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calcium ion binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

protein binding

determination method

1 reference

8 April 2019

Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

serine-type peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

serine-type endopeptidase activity

determination method

4 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

enzyme activator activity

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

extracellular matrix

determination method

1 reference

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

biological process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

thrombin-activated receptor signaling pathway

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

determination method

2 references

platelet activation

determination method

3 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

8 April 2019

Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

positive regulation of cell growth

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

acute-phase response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

regulation of cell shape

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

regulation of gene expression

determination method

1 reference

8 April 2019

Impaired "outside-in" integrin alphaIIbbeta3 signaling and thrombus stability in TSSC6-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

positive regulation of phosphatidylinositol 3-kinase signaling

determination method

1 reference

8 April 2019

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19221

determination method

blood coagulation

determination method

4 references

14 January 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

14 January 2019

Administration of factor XIII B subunit increased plasma factor XIII A subunit levels in factor XIII B subunit knock-out mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

blood coagulation, fibrin clot formation

determination method

1 reference

14 January 2019

Administration of factor XIII B subunit increased plasma factor XIII A subunit levels in factor XIII B subunit knock-out mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19221&geneProductId=UniProtKB:P19221

determination method

serine proteases, trypsin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Serine proteases, trypsin family, serine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

thrombin light chain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

gamma-carboxyglutamic acid-rich (GLA) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

kringle, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

serine proteases, trypsin family, histidine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19221

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000028681

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000028681

ENSMUSP00000106967

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000106967

PDB structure ID

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

1 reference

UniProt protein ID

10 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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