(Q14866083)

English

Dopamine receptor D4

mammalian protein found in Mus musculus

dopamine D4 receptor
dopamine receptor 4
D(4) dopamine receptor
d(2C) dopamine receptor
Drd4

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Dopamine D4 receptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51436

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

dopamine neurotransmitter receptor activity

determination method

3 references

signal transducer activity

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

dopamine neurotransmitter receptor activity, coupled via Gi/Go

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Dopamine D4 receptor-deficient mice display cortical hyperexcitability

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

dopamine binding

determination method

3 references

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

G protein-coupled receptor activity

determination method

G protein-coupled serotonin receptor activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

neurotransmitter receptor activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

integral component of membrane

determination method

2 references

determination method

3 references

plasma membrane

determination method

3 references

integral component of plasma membrane

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

vesicle membrane

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51436&geneProductId=UniProtKB:P51436

determination method

neuronal cell body

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

terminal bouton

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

dendritic spine

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

integral component of plasma membrane

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

glutamatergic synapse

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

GABA-ergic synapse

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

integral component of postsynaptic membrane

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

integral component of presynaptic membrane

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

biological process

G protein-coupled receptor signaling pathway

determination method

2 references

determination method

1 reference

14 February 2019

Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

rhythmic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

adult locomotory behavior

determination method

1 reference

14 February 2019

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

response to amphetamine

determination method

1 reference

14 February 2019

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of dopamine metabolic process

determination method

1 reference

14 February 2019

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of circadian rhythm

determination method

1 reference

14 February 2019

Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

signal transduction

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

adenylate cyclase-inhibiting dopamine receptor signaling pathway

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Dopamine D4 receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus pallidus neurons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

behavioral fear response

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

synaptic transmission, dopaminergic

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

short-term memory

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

associative learning

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

olfactory learning

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of neurotransmitter secretion

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

modulation of chemical synaptic transmission

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of calcium-mediated signaling

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

positive regulation of penile erection

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

negative regulation of vascular associated smooth muscle cell proliferation

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

negative regulation of vascular associated smooth muscle cell migration

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

positive regulation of excitatory postsynaptic potential

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

chemical synaptic transmission

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

G protein-coupled serotonin receptor signaling pathway

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of postsynaptic membrane neurotransmitter receptor levels

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of postsynaptic neurotransmitter receptor internalization

determination method

3 references

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

14 February 2019

Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

regulation of synaptic vesicle exocytosis

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51436

determination method

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51436

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000026569

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000026569

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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