(Q14878201)

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

interleukin-1 receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

1 reference

14 February 2019

cell component

cytosol

1 reference

24 April 2018

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

6 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

14 February 2019

Gene from a psoriasis susceptibility locus primes the skin for inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

cell surface

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

cellular response to heat

biological process

ISS

response to copper ion

ISS

positive regulation of angiogenesis

1 reference

14 February 2019

IL-1 is required for tumor invasiveness and angiogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

1 reference

14 February 2019

connective tissue replacement involved in inflammatory response wound healing

1 reference

14 February 2019

Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

extrinsic apoptotic signaling pathway in absence of ligand

1 reference

14 February 2019

Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

ectopic germ cell programmed cell death

1 reference

14 February 2019

Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of vascular endothelial growth factor production

1 reference

14 February 2019

IL-1 is required for tumor invasiveness and angiogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

1 reference

14 February 2019

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

fever generation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

1 reference

14 February 2019

positive regulation of neutrophil extravasation

1 reference

24 April 2018

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

24 April 2018

24 April 2018

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

interleukin-1-mediated signaling pathway

1 reference

24 April 2018

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

positive regulation of monocyte chemotactic protein-1 production

1 reference

24 April 2018

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01582&geneProductId=UniProtKB:P01582

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of steroid biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

keratinization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of prostaglandin secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of stress-activated MAPK cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

regulation of actin cytoskeleton organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of JNK cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

regulation of sensory perception of pain

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of neutrophil migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

negative regulation of establishment of Sertoli cell barrier

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

positive regulation of interleukin-6 production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01582

has part(s)

Interleukin-1 propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01582

Interleukin-1 conserved site

1 reference

InterPro Release 71.0