Wikidata

(Q14888116)

English

Trans-acting transcription factor 1

mammalian protein found in Mus musculus

  • Sp1
  • uniprot:O89090
  • transcription factor Sp1
  • specificity protein 1
In more languages

Statements

molecular function
DNA binding
determination method
IDA
ISS
IEA
ISO
12 references
retrieved
14 February 2019
stated in
Mammalian SP/KLF transcription factors: bring in the family
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
14 February 2019
stated in
Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Transcriptional regulation of murine beta1,4-galactosyltransferase in somatic cells. Analysis of a gene that serves both a housekeeping and a mammary gland-specific function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Regulation of aldehyde reductase expression by STAF and CHOP
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
RNA polymerase II cis-regulatory region sequence-specific DNA binding
determination method
IDA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
ISO
retrieved
14 February 2019
stated in
Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
DNA-binding transcription factor activity
determination method
IDA
IEA
IMP
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
ISO
retrieved
14 February 2019
stated in
Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
14 February 2019
stated in
NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
cell component
nucleus
determination method
IDA
IEA
ISO
11 references
retrieved
5 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
ISO
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
5 June 2018
stated in
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
A far upstream, cell type-specific enhancer of the mouse thrombospondin 3 gene is located within intron 6 of the adjacent metaxin gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
5 June 2018
stated in
Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
ISO
12 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IEA
retrieved
14 February 2019
stated in
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury
GOA
curator
UniProt
UniProt protein ID
O89090
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
A far upstream, cell type-specific enhancer of the mouse thrombospondin 3 gene is located within intron 6 of the adjacent metaxin gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090
determination method
IBA
biological process

Identifiers

 
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