(Q14890657)

English

Apolipoprotein B

mammalian protein found in Mus musculus

uniprot:E9Q414
Apob
apolipoprotein B-100

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Lipovitellin-phosvitin complex, superhelical domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q414

Vitellinogen, beta-sheet N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q414

Lipid transport protein, beta-sheet shell

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q414

Lipid transport protein, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Lipid transport, open beta-sheet, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vitellinogen, open beta-sheet, protein family

1 reference

based on heuristic

inferred from protein domain or family

Apolipoprotein B100 C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

heparin binding

determination method

3 references

lipid transporter activity

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

determination method

1 reference

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q414&geneProductId=UniProtKB:E9Q414

determination method

signaling receptor binding

determination method

1 reference

14 January 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q414&geneProductId=UniProtKB:E9Q414

determination method

determination method

3 references

determination method

3 references

very-low-density lipoprotein particle

determination method

3 references

endoplasmic reticulum

determination method

1 reference

14 February 2019

Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

low-density lipoprotein particle

determination method

3 references

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

extracellular region

determination method

vesicle membrane

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

extracellular region

determination method

2 references

high-density lipoprotein particle

determination method

1 reference

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q414&geneProductId=UniProtKB:E9Q414

determination method

biological process

lipoprotein metabolic process

determination method

6 references

14 February 2019

Regulation of the apolipoprotein B in heterozygous hypobetalipoproteinemic knock-out mice expressing truncated apoB, B81. Low production and enhanced clearance of apoB cause low levels of apoB

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Hepatic secretion of apoB-100 is impaired in hypobetalipoproteinemic mice with an apoB-38.9-specifying allele

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

cellular response to prostaglandin stimulus

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

flagellated sperm motility

determination method

1 reference

14 February 2019

A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

steroid metabolic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

response to selenium ion

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

lipid transport

determination method

2 references

cholesterol transport

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

regulation of cholesterol biosynthetic process

determination method

1 reference

14 February 2019

A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

cellular response to tumor necrosis factor

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

response to virus

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

cholesterol metabolic process

determination method

3 references

in utero embryonic development

determination method

2 references

14 February 2019

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

post-embryonic development

determination method

1 reference

14 February 2019

A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

response to organic substance

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

nervous system development

determination method

3 references

14 February 2019

Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

lipoprotein catabolic process

determination method

1 reference

14 February 2019

Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

lipid catabolic process

determination method

1 reference

14 February 2019

A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

response to lipopolysaccharide

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

positive regulation of gene expression

determination method

1 reference

14 February 2019

Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

spermatogenesis

determination method

1 reference

14 February 2019

A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

artery morphogenesis

determination method

1 reference

14 February 2019

Delayed arteriogenesis in hypercholesterolemic mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

cholesterol efflux

determination method

1 reference

14 February 2019

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

determination method

1 reference

14 February 2019

A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

lipoprotein biosynthetic process

determination method

1 reference

14 February 2019

Hepatic secretion of apoB-100 is impaired in hypobetalipoproteinemic mice with an apoB-38.9-specifying allele

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

cholesterol homeostasis

determination method

9 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Delayed arteriogenesis in hypercholesterolemic mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

triglyceride mobilization

determination method

1 reference

14 February 2019

A targeted apolipoprotein B-38.9-producing mutation causes fatty livers in mice due to the reduced ability of apolipoprotein B-38.9 to transport triglycerides

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

response to estradiol

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

lipid metabolism

determination method

7 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Reduced intestinal fat absorptive capacity but enhanced susceptibility to diet-induced fatty liver in mice heterozygous for ApoB38.9 truncation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

triglyceride catabolic process

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q414

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000036044

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000036044

ENSMUSP00000035761

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000035761

ENSMUSP00000127147

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000127147

ENSMUSP00000129496

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000129496

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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