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Bone morphogenetic protein 8a
mammalian protein found in Mus musculus
bone morphogenetic protein 8A
OP-2
Bmp8a
osteogenic protein 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P34821
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P34821
part of
Transforming growth factor-beta-related
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34821
Cystine-knot cytokine
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34821
Transforming growth factor-beta, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
TGF-beta, propeptide family
1 reference
based on heuristic
inferred from protein domain or family
Transforming growth factor beta, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P34821
encoded by
Bmp8a
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P34821
molecular function
cytokine activity
determination method
TAS
IEA
2 references
retrieved
27 March 2018
stated in
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P34821&geneProductId=UniProtKB:P34821
determination method
TAS
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P34821&geneProductId=UniProtKB:P34821
determination method
IEA
BMP receptor binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
transforming growth factor beta receptor binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
growth factor activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
cytokine activity
determination method
IBA
IEA
TAS
3 references
retrieved
14 February 2019
stated in
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
extracellular space
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
biological process
regulation of apoptotic process
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
germ cell development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Requirement ofBmp8bfor the Generation of Primordial Germ Cells in the Mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IMP
cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
negative regulation of insulin secretion
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
ISO
regulation of MAPK cascade
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
SMAD protein signal transduction
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
ossification
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
positive regulation of pathway-restricted SMAD protein phosphorylation
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
BMP signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
diet induced thermogenesis
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
ISO
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
cartilage development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
osteoblast differentiation
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
GOA
curator
UniProt
UniProt protein ID
P34821
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IDA
spermatogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IMP
transforming growth factor beta receptor signaling pathway
determination method
TAS
1 reference
retrieved
14 February 2019
stated in
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
TAS
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IEA
energy homeostasis
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
ISO
cell development
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34821
determination method
IBA
has part(s)
Transforming growth factor beta, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34821
Transforming growth factor-beta, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34821
TGF-beta, propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P34821
Identifiers
RefSeq protein ID
NP_001242948
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
12163
NP_031584
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
12163
UniProt protein ID
P34821
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P34821
Ensembl protein ID
ENSMUSP00000099701
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000099701
ENSMUSP00000037779
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000037779
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