(Q14905597)

http://www.ebi.ac.uk/interpro/protein/O35690

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

2 references

sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

1 January 2018

The Hlx homeobox transcription factor is required early in enteric nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

1 January 2018

Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

1 January 2018

A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

The Hlx homeobox transcription factor is required early in enteric nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

sympathetic ganglion development

IBA

biological process

1 reference

14 February 2019

Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

noradrenergic neuron development

1 reference

14 February 2019

Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

dopaminergic neuron differentiation

1 reference

14 February 2019

The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

negative regulation of neuron differentiation

1 reference

14 February 2019

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

sympathetic nervous system development

IGI

1 reference

14 February 2019

The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

1 reference

14 February 2019

The role of Phox2B in chromaffin cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

parasympathetic nervous system development

1 reference

14 February 2019

The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

retrotrapezoid nucleus neuron differentiation

1 reference

14 February 2019

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

brainstem development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

cellular response to BMP stimulus

1 reference

14 February 2019

BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

1 reference

14 February 2019

Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

glial cell differentiation

1 reference

14 February 2019

Signals from the neural crest regulate beta-cell mass in the pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

efferent axon development in a lateral line nerve

1 reference

14 February 2019

Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

regulation of respiratory gaseous exchange by nervous system process

1 reference

14 February 2019

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

cell differentiation in hindbrain

1 reference

14 February 2019

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

neural crest cell migration involved in autonomic nervous system development

1 reference

14 February 2019

The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

positive regulation of neuron differentiation

1 reference

14 February 2019

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

Signals from the neural crest regulate beta-cell mass in the pancreas

IGI

neuron differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

respiratory system development

1 reference

14 February 2019

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

skeletal muscle cell differentiation

1 reference

14 February 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

regulation of gene expression

1 reference

14 February 2019

Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus

inner ear development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

medullary reticular formation development

1 reference

14 February 2019

Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

hindbrain tangential cell migration

IEP

1 reference

14 February 2019

Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

Genomic structure and functional characterization of NBPhox (PMX2B), a homeodomain protein specific to catecholaminergic cells that is involved in second messenger-mediated transcriptional activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

negative regulation of cell population proliferation

IDA

1 reference

14 February 2019

Signals from the neural crest regulate beta-cell mass in the pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

transcription by RNA polymerase II

1 reference

31 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35690&geneProductId=UniProtKB:O35690

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn phox2b heterozygous knock-out mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

nervous system development

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

autonomic nervous system development

IBA

3 references

enteric nervous system development

3 references

14 February 2019

The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35690

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35690

Homeobox, conserved site

1 reference

stated in

InterPro Release 71.0