(Q14908106)
English
TSC1-TSC2 complex
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.
- GO:0033596
- tuberous sclerosis complex
- tuberin-hamartin complex
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