(Q14910072)

English

Apolipoprotein A-I

mammalian protein found in Mus musculus

apolipoprotein A-I
Apoa1
apolipoprotein A1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Apolipoprotein A/E

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q00623

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

phosphatidylcholine binding

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

high-density lipoprotein particle receptor binding

determination method

3 references

lipoprotein particle binding

determination method

1 reference

14 February 2019

Structural and functional properties of human and mouse apolipoprotein A-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

phosphatidylcholine-sterol O-acyltransferase activator activity

determination method

3 references

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol transfer activity

determination method

3 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

protein binding

determination method

3 references

14 February 2019

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol binding

determination method

3 references

identical protein binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Structural and functional properties of human and mouse apolipoprotein A-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

phospholipid transporter activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

lipase inhibitor activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

phospholipid binding

determination method

3 references

cholesterol transfer activity

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

signaling receptor binding

determination method

1 reference

14 January 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

endocytic vesicle

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

high-density lipoprotein particle

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

extracellular space

determination method

14 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Abnormal phospholipid composition impairs HDL biogenesis and maturation in mice lacking Abca1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

SAA-only HDL formed during the acute phase response in apoA-I+/+ and apoA-I-/- mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Dietary fatty acids and dietary cholesterol differ in their effect on the in vivo regulation of apolipoprotein A-I and A-II gene expression in inbred strains of mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

extracellular region

determination method

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

blood microparticle

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

extracellular matrix

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

low-density lipoprotein particle

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

intermediate-density lipoprotein particle

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

discoidal high-density lipoprotein particle

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

extracellular region

determination method

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

biological process

regulation of protein phosphorylation

determination method

1 reference

14 February 2019

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

lipid transport

determination method

2 references

positive regulation of cholesterol esterification

determination method

3 references

phospholipid efflux

determination method

3 references

negative regulation of hydrolase activity

determination method

1 reference

14 February 2019

Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

regulation of intestinal cholesterol absorption

determination method

1 reference

14 February 2019

ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

endothelial cell proliferation

determination method

1 reference

14 February 2019

High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

peptidyl-methionine modification

determination method

3 references

lipoprotein biosynthetic process

determination method

cholesterol homeostasis

determination method

3 references

axon regeneration

determination method

1 reference

14 February 2019

Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

positive regulation of fatty acid biosynthetic process

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

very-low-density lipoprotein particle remodeling

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

lipoprotein metabolic process

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

positive regulation of triglyceride catabolic process

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

glucocorticoid metabolic process

determination method

1 reference

14 February 2019

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

determination method

1 reference

14 February 2019

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

positive regulation of lipoprotein lipase activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

cholesterol metabolic process

determination method

10 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

The acute phase response in apolipoprotein A-1 knockout mice: apolipoprotein serum amyloid A and lipid distribution in plasma high density lipoproteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

HDL deficiency in genetically engineered mice requires elevated LDL to accelerate atherogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

SAA-only HDL formed during the acute phase response in apoA-I+/+ and apoA-I-/- mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance?

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

triglyceride catabolic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol efflux

determination method

7 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

24 April 2018

ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

phosphatidylcholine metabolic process

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

protein localization

determination method

1 reference

14 February 2019

Apolipoprotein E and apolipoprotein A-1 knock-out mice readily develop amyloid A protein amyloidosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

steroid metabolic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

blood vessel endothelial cell migration

determination method

1 reference

14 February 2019

High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

lipid metabolism

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol transport

determination method

5 references

14 February 2019

Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

adrenal gland development

determination method

1 reference

14 February 2019

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

high-density lipoprotein particle assembly

determination method

3 references

phospholipid metabolic process

determination method

1 reference

14 February 2019

The acute phase response in apolipoprotein A-1 knockout mice: apolipoprotein serum amyloid A and lipid distribution in plasma high density lipoproteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

vitamin transport

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol biosynthetic process

determination method

1 reference

24 April 2018

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

triglyceride homeostasis

determination method

reverse cholesterol transport

determination method

3 references

neuron projection regeneration

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623

determination method

phospholipid transport

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

animal organ regeneration

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

negative regulation of lipase activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

regulation of cholesterol transport

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

cholesterol efflux

determination method

8 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

positive regulation of lipid biosynthetic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623

determination method

protein stabilization

determination method

3 references

positive regulation of cholesterol efflux

determination method

3 references

positive regulation of phagocytosis

determination method

3 references

positive regulation of phospholipid efflux

determination method

3 references

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000034588

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000034588

ENSMUSP00000150525

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000150525

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

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