(Q14911719)

DNA mismatch repair protein MutS, core domain superfamily

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

MutS, connector domain superfamily

1 reference

DNA mismatch repair protein MutS, connector domain, protein family

1 reference

DNA mismatch repair protein MutS, C-terminal domain, protein family

1 reference

DNA mismatch repair protein MutS, clamp, protein family

1 reference

DNA mismatch repair protein MutS, core domain, protein family

1 reference

PWWP domain, protein family

1 reference

DNA mismatch repair protein MutS-like, N-terminal domain, protein family

1 reference

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

1 reference

25 May 2022

1 reference

25 May 2022

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

mismatched DNA binding

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

1 reference

9 May 2019

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

methylated histone binding

IDA

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

guanine/thymine mispair binding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

four-way junction DNA binding

IDA

ATP-dependent activity, acting on DNA

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

single base insertion or deletion binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

3 references

8 April 2019

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

guanine/thymine mispair binding

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

single thymine insertion binding

MutLalpha complex binding

methylated histone binding

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

mismatched DNA binding

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

oxidized purine DNA binding

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

mismatch repair complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

somatic hypermutation of immunoglobulin genes

biological process

4 references

8 April 2019

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

8 April 2019

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

cellular response to DNA damage stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

positive regulation of isotype switching

1 reference

14 February 2019

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

intrinsic apoptotic signaling pathway

IGI

1 reference

9 May 2019

DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

somatic recombination of immunoglobulin gene segments

1 reference

8 April 2019

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

27 March 2018

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

1 reference

14 February 2019

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

negative regulation of DNA recombination

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

10 references

27 March 2018

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54276&geneProductId=UniProtKB:P54276

1 reference

9 May 2019

DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

maintenance of DNA repeat elements

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

meiotic mismatch repair

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

pyrimidine dimer repair

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

11 references

9 May 2019

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

mitotic G2 DNA damage checkpoint signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

negative regulation of DNA endoreduplication

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

interstrand cross-link repair

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

replication fork arrest

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

negative regulation of DNA recombination

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

positive regulation of helicase activity

somatic hypermutation of immunoglobulin genes

5 references

9 May 2019

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54276

somatic recombination of immunoglobulin gene segments

DNA mismatch repair protein MutS, C-terminal

1 reference

DNA mismatch repair protein MutS, clamp

1 reference

DNA mismatch repair protein MutS, connector domain

1 reference

DNA mismatch repair protein MutS-like, N-terminal

1 reference

DNA mismatch repair protein MutS, core

1 reference

PWWP domain

1 reference