(Q15313262)

Zinc finger, NHR/GATA-type

1 reference

nuclear receptor

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

3 references

sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

DNA-binding transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

DNA-binding transcription activator activity, RNA polymerase II-specific

histone deacetylase binding

IDA

1 reference

14 February 2019

Histone demethylase LSD1 regulates neural stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

steroid hormone receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

24 April 2018

The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64104&geneProductId=UniProtKB:Q64104

24 April 2018

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64104&geneProductId=UniProtKB:Q64104

14 February 2019

The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Histone demethylase LSD1 regulates neural stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

negative regulation of astrocyte differentiation

IGI

1 reference

14 February 2019

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

negative regulation of neuron differentiation

4 references

14 February 2019

Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Loss of the tailless gene affects forebrain development and emotional behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

somatic stem cell population maintenance

3 references

14 February 2019

Loss of the tailless gene affects forebrain development and emotional behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

regulation of cellular component organization

1 reference

14 February 2019

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

extracellular matrix organization

1 reference

14 February 2019

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

negative regulation of apoptotic process

1 reference

14 February 2019

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

negative regulation of transcription by RNA polymerase II

4 references

14 February 2019

The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Histone demethylase LSD1 regulates neural stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

Loss of the tailless gene affects forebrain development and emotional behavior

IDA

behavioral fear response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

regulation of timing of neuron differentiation

1 reference

14 February 2019

The Tlx gene regulates the timing of neurogenesis in the cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64104&geneProductId=UniProtKB:Q64104

positive regulation of angiogenesis

1 reference

14 February 2019

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

anterior commissure morphogenesis

1 reference

14 February 2019

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

regulation of dendrite morphogenesis

1 reference

14 February 2019

Deletion of the nuclear receptor Nr2e1 impairs synaptic plasticity and dendritic structure in the mouse dentate gyrus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

positive regulation of neural precursor cell proliferation

1 reference

14 February 2019

Histone demethylase LSD1 regulates neural stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

positive regulation of cell cycle

1 reference

14 February 2019

Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Loss of the tailless gene affects forebrain development and emotional behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

forebrain generation of neurons

1 reference

14 February 2019

Defective limbic system in mice lacking the tailless gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

layer formation in cerebral cortex

1 reference

14 February 2019

The Tlx gene regulates the timing of neurogenesis in the cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

cerebral cortex development

4 references

14 February 2019

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Abnormal development of zinc-containing cortical circuits in the absence of the transcription factor Tailless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Pathological aggression in "fierce" mice corrected by human nuclear receptor 2E1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Loss of the tailless gene affects forebrain development and emotional behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

regulation of cell migration involved in sprouting angiogenesis

1 reference

14 February 2019

Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

positive regulation of stem cell proliferation

1 reference

14 February 2019

Histone demethylase LSD1 regulates neural stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

4 references

14 February 2019

Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Loss of the tailless gene affects forebrain development and emotional behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Pathological aggression in "fierce" mice corrected by human nuclear receptor 2E1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

14 February 2019

Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

1 reference

14 February 2019

Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

steroid hormone mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

Deletion of the nuclear receptor Nr2e1 impairs synaptic plasticity and dendritic structure in the mouse dentate gyrus

long-term potentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64104

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64104&geneProductId=UniProtKB:Q64104

Nuclear hormone receptor, ligand-binding domain

has part(s)

1 reference

nuclear hormone receptor-type zinc finger

1 reference