(Q15333021)

Winged helix-like DNA-binding domain superfamily

1 reference

E2F family

1 reference

E2F-DP heterodimerization region

1 reference

E2F/DP family, winged-helix DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

E2F transcription factor, CC-MB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

3 references

7 November 2018

Heregulin regulates the ability of the ErbB3-binding protein Ebp1 to bind E2F promoter elements and repress E2F-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

DNA-binding transcription factor activity

7 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

transcription factor binding

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

Association of Pur alpha and E2F-1 suppresses transcriptional activity of E2F-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

The DP-1 transcription factor is required for keratinocyte growth and epidermal stratification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

protein dimerization activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

sequence-specific DNA binding

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

DNA-binding transcription factor activity, RNA polymerase II-specific

cis-regulatory region sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

DNA-binding transcription factor activity, RNA polymerase II-specific

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

transcription factor binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Association of Pur alpha and E2F-1 suppresses transcriptional activity of E2F-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

sequence-specific DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

4 references

14 February 2019

Heregulin regulates the ability of the ErbB3-binding protein Ebp1 to bind E2F promoter elements and repress E2F-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

DNA-binding transcription factor activity

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

5 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

7 November 2018

C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

3 references

RNA polymerase II transcription regulator complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

negative regulation of fat cell differentiation

biological process

1 reference

14 February 2019

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

regulation of transcription, DNA-templated

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

lens fiber cell apoptotic process

1 reference

14 February 2019

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

negative regulation of fat cell proliferation

1 reference

14 February 2019

Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

cellular response to xenobiotic stimulus

IMP

1 reference

14 February 2019

RB tumor suppressive function in response to xenobiotic hepatocarcinogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

DNA damage checkpoint signaling

3 references

regulation of cell cycle

1 reference

21 June 2018

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

positive regulation of transcription, DNA-templated

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

cellular response to fatty acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

1 reference

14 February 2019

Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

intrinsic apoptotic signaling pathway by p53 class mediator

1 reference

14 February 2019

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

Developmental roles of p73 in Cajal-Retzius cells and cortical patterning

forebrain development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

cellular response to hypoxia

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

positive regulation of transcription by RNA polymerase II

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

Ei24, a novel E2F target gene, affects p53-independent cell death upon ultraviolet C irradiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

21 June 2018

Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61501&geneProductId=UniProtKB:Q61501

negative regulation of transcription by RNA polymerase II

3 references

transcription, DNA-templated

1 reference

14 February 2019

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

positive regulation of transcription by RNA polymerase II

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Ei24, a novel E2F target gene, affects p53-independent cell death upon ultraviolet C irradiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61501

E2F transcription factor, CC-MB domain

has part(s)

1 reference

E2F/DP family, winged-helix DNA-binding domain

1 reference