(Q15335644)

Manganese/iron superoxide dismutase, N-terminal domain superfamily

1 reference

Manganese/iron superoxide dismutase

1 reference

Manganese/iron superoxide dismutase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Manganese/iron superoxide dismutase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Manganese/iron superoxide dismutase, binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

12 September 2018

1 reference

12 September 2018

superoxide dismutase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

12 references

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis?

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Mouse mitochondrial superoxide dismutase locus is on chromosome 17

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

An unexpected functional link between lysosomal thiol reductase and mitochondrial manganese superoxide dismutase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Developmental changes in murine brain antioxidant enzymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

manganese ion binding

ISS

3 references

oxidoreductase activity

enzyme binding

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

oxygen binding

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

DNA binding

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

protein binding

IPI

1 reference

14 February 2019

Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

superoxide dismutase activity

IPI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

13 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

An unexpected functional link between lysosomal thiol reductase and mitochondrial manganese superoxide dismutase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Developmental changes in murine brain antioxidant enzymes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Mouse mitochondrial superoxide dismutase locus is on chromosome 17

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

manganese ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

cell component

myelin sheath

1 reference

31 January 2018

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

mitochondrion

12 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

31 January 2018

Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

mitochondrial inner membrane

1 reference

31 January 2018

Proteomic analysis of the mouse liver mitochondrial inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

mitochondrial nucleoid

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

cytoplasm

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

mitochondrion

13 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

mitochondrial inner membrane

1 reference

14 February 2019

Proteomic analysis of the mouse liver mitochondrial inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

myelin sheath

1 reference

14 February 2019

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

negative regulation of neuron apoptotic process

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to immobilization stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

intrinsic apoptotic signaling pathway in response to oxidative stress

1 reference

14 February 2019

Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

hemopoiesis

negative regulation of fat cell differentiation

1 reference

14 February 2019

Adipocyte differentiation in Sod2(-/-) and Sod2(+/+) murine bone marrow stromal cells is associated with low antioxidant pools

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to selenium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

erythrophore differentiation

1 reference

14 February 2019

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to hypoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to superoxide

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Prolonged hypoxia during cell development protects mature manganese superoxide dismutase-deficient astrocytes from damage by oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to cadmium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

glutathione metabolic process

1 reference

14 February 2019

Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

cellular response to ethanol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

locomotory behavior

1 reference

14 February 2019

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to magnetism

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to reactive oxygen species

5 references

14 February 2019

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Adipocyte differentiation in Sod2(-/-) and Sod2(+/+) murine bone marrow stromal cells is associated with low antioxidant pools

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Mitochondrial disease in superoxide dismutase 2 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

3 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

removal of superoxide radicals

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to hyperoxia

1 reference

14 February 2019

Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure

1 reference

14 February 2019

MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

positive regulation of nitric oxide biosynthetic process

1 reference

14 February 2019

Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

iron ion homeostasis

1 reference

14 February 2019

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

ageing

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

mitochondrion organization

3 references

14 February 2019

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Ocular pathology in mitochondrial superoxide dismutase (Sod2)-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

vasodilation

1 reference

14 February 2019

Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

neuron development

1 reference

14 February 2019

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to zinc ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to L-ascorbic acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

hearing

1 reference

14 February 2019

Effects of antioxidants on the aging inner ear

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

post-embryonic development

response to electrical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to oxidative stress

Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

detection of oxygen

1 reference

14 February 2019

Prolonged hypoxia during cell development protects mature manganese superoxide dismutase-deficient astrocytes from damage by oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to isolation stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

superoxide anion generation

3 references

14 February 2019

Limited exercise capacity in heterozygous manganese superoxide dismutase gene-knockout mice: roles of superoxide anion and nitric oxide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

regulation of blood pressure

1 reference

14 February 2019

Association of mitochondrial SOD deficiency with salt-sensitive hypertension and accelerated renal senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

regulation of mitochondrial membrane potential

1 reference

14 February 2019

Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

heart development

1 reference

14 February 2019

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to manganese ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

apoptotic mitochondrial changes

1 reference

14 February 2019

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to axon injury

1 reference

14 February 2019

Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

14 February 2019

Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to silicon dioxide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to cold

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

liver development

1 reference

14 February 2019

Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to radiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

respiratory electron transport chain

2 references

14 February 2019

Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

regulation of catalytic activity

1 reference

14 February 2019

Mitochondrial disease in superoxide dismutase 2 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

response to gamma radiation

1 reference

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

negative regulation of fibroblast proliferation

1 reference

14 February 2019

An unexpected functional link between lysosomal thiol reductase and mitochondrial manganese superoxide dismutase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

protein homotetramerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

oxygen homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

release of cytochrome c from mitochondria

2 references

14 February 2019

Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

superoxide metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

6 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

14 February 2019

negative regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

hydrogen peroxide metabolic process

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

response to nutrient levels

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

hydrogen peroxide biosynthetic process

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

protein homooligomerization

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

negative regulation of apoptotic process

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09671&geneProductId=UniProtKB:P09671

positive regulation of cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

positive regulation of vascular associated smooth muscle cell apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09671

Manganese/iron superoxide dismutase, C-terminal

has part(s)

1 reference

Manganese/iron superoxide dismutase, N-terminal

1 reference

Manganese/iron superoxide dismutase, binding site

1 reference