(Q21032449)

dihydroartemisinin/piperaquine

ChEBI release 2020-05-28

ChEBI ID

91231

1 reference

Gillian M. Keating

1

Gillian M

Keating

1 reference

PubMed publication ID

22515619

Clinical pharmacology of artemisinin-based combination therapies

27 July 2022

language of work or name

English

0 references

publication date

May 2012

0 references

published in

Drugs

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volume

72

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issue

7

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page(s)

937-961

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cites work

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Yeast model uncovers dual roles of mitochondria in action of artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Piperaquine: a resurgent antimalarial drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Role of known molecular markers of resistance in the antimalarial potency of piperaquine and dihydroartemisinin in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Antimalarial efficacy of piperaquine-based antimalarial combination therapies: facts and uncertainties

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemisinin Resistance in Plasmodium falciparum Malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

In vitro activities of piperaquine and other 4-aminoquinolines against clinical isolates of Plasmodium falciparum in Cameroon

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

In vitro interactions between piperaquine, dihydroartemisinin, and other conventional and novel antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Cardiotoxicity of antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A small amount of fat does not affect piperaquine exposure in patients with malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Effects of a high-fat meal on the relative oral bioavailability of piperaquine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

The influence of food on the pharmacokinetics of piperaquine in healthy Vietnamese volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Measurement of piperaquine in plasma by liquid chromatography with ultraviolet absorbance detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Dihydroartemisinin-piperaquine versus artemether-lumefantrine, in the treatment of uncomplicated Plasmodium falciparum malaria in central Sudan

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for falciparum malaria: a longitudinal, randomized trial in young Ugandan children

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Randomized trials of artemisinin-piperaquine, dihydroartemisinin-piperaquine phosphate and artemether-lumefantrine for the treatment of multi-drug resistant falciparum malaria in Cambodia-Thailand border area

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A trial of combination antimalarial therapies in children from Papua New Guinea.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Artemisinin combination therapy for vivax malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Efficacy and safety of dihydroartemisinin-piperaquine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Diagnosis and therapy for hospitalized imported malaria in adults in Italy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Counterfeit or substandard antimicrobial drugs: a review of the scientific evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Efficacy, safety, and tolerability of three regimens for prevention of malaria: a randomized, placebo-controlled trial in Ugandan schoolchildren

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

A randomised trial to compare the safety, tolerability and efficacy of three drug combinations for intermittent preventive treatment in children

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Adverse pregnancy outcomes in an area where multidrug-resistant plasmodium vivax and Plasmodium falciparum infections are endemic

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11203910-000000000-00000

Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria.

21 January 2018

1 reference

12 December 2020

An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria.

1 reference

12 December 2020

Pharmacokinetics of the antimalarial drug piperaquine in healthy Vietnamese subjects.

1 reference

12 December 2020

In vitro cardiovascular effects of dihydroartemisin-piperaquine combination compared with other antimalarials

1 reference

12 December 2020

Artemisinin resistance: current status and scenarios for containment

1 reference

12 December 2020

Dihydroartemisinin-piperaquine rescue treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy: a preliminary report

1 reference

12 December 2020

10.2165/11203910-000000000-00000

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

285164

Dimensions Publication ID

1020212832

0 references

OpenCitations bibliographic resource ID

285164

1 reference