(Q21097293)

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

identical protein binding

double-stranded DNA binding

IPI

1 reference

1 January 2018

IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

transcription factor binding

7 references

1 January 2018

The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

IFI16 is an innate immune sensor for intracellular DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

6 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

17 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

2 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

positive regulation of type I interferon production

HDA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

positive regulation of cytokine production

TAS

1 reference

1 January 2018

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

intrinsic apoptotic signaling pathway by p53 class mediator

TAS

1 reference

1 January 2018

IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

cellular response to glucose starvation

1 reference

1 January 2018

IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

transcription, DNA-templated

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

negative regulation of viral genome replication

1 reference

1 January 2018

The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

negative regulation of innate immune response

1 reference

1 January 2018

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations

monocyte differentiation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

cellular response to ionizing radiation

1 reference

1 January 2018

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

negative regulation of DNA binding

1 reference

1 January 2018

The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway

regulation of autophagy

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

myeloid cell differentiation

IEP

1 reference

1 January 2018

IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

NAS

1 reference

1 January 2018

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

activation of cysteine-type endopeptidase activity

NAS

1 reference

1 January 2018

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

negative regulation of cysteine-type endopeptidase activity

1 reference

1 January 2018

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

negative regulation of transcription by RNA polymerase II

3 references

1 January 2018

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

positive regulation of interleukin-1 beta production

1 reference

1 January 2018

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

regulation of transcription, DNA-templated

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

regulation of gene expression, epigenetic

1 reference

1 January 2018

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

cell population proliferation

1 reference

1 January 2018

The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

positive regulation of transcription by RNA polymerase II

NAS

activation of innate immune response

1 reference

17 October 2017

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

immune system process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

inflammatory response

1 reference

1 January 2018

negative regulation of transcription, DNA-templated

1 reference

1 January 2018

The human interferon-inducible protein, IFI 16, is a repressor of transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

innate immune response

1 reference

1 January 2018

defense response to virus

1 reference

1 January 2018

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

cellular response to interferon-beta

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016