(Q21097595)

English

Autophagy related 3

mammalian protein found in Homo sapiens

APG3-like
ubiquitin-like-conjugating enzyme ATG3
2610016C12Rik
autophagy-related protein 3
ATG3 autophagy related 3 homolog
hApg3
APG3 autophagy 3-like
Protein PC3-96
ATG3

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Statements

1 reference

13 November 2019

1 reference

Transporter Classification Database ID

9.A.15.2.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Autophagy-related protein 3 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

ubiquitin-like protein transferase activity

1 reference

8 April 2019

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

1 reference

8 April 2019

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

6 references

8 April 2019

Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Network organization of the human autophagy system

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NT62&geneProductId=UniProtKB:Q9NT62

10 September 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NT62&geneProductId=UniProtKB:Q9NT62

10 September 2018

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NT62&geneProductId=UniProtKB:Q9NT62

determination method

IDA

cytoplasmic ubiquitin ligase complex

1 reference

27 February 2018

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NT62&geneProductId=UniProtKB:Q9NT62

determination method

IPI

cytoplasmic ubiquitin ligase complex

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NT62&geneProductId=UniProtKB:Q9NT62

determination method

IBA

autophagy of mitochondrion

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

determination method

IBA

autophagosome assembly

3 references

protein ubiquitination

1 reference

8 April 2019

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

determination method

IDA

protein targeting to membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

determination method

ISS

negative regulation of phagocytosis

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NT62

determination method

IEA

has part(s)

Autophagy-related protein 3

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9NT62

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

English

Transporter Classification Database ID

9.A.15.2.1

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

(Q21097595)

Autophagy related 3

Statements

Identifiers

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