(Q21100505)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q10589

image

Protein BST2 PDB 2X7A.png
1,200 × 1,000; 265 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

1 reference

17 October 2017

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

signal transducer activity

1 reference

17 October 2017

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

protein binding

6 references

17 October 2017

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

metalloendopeptidase inhibitor activity

1 reference

17 October 2017

BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

RNA binding

1 reference

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

identical protein binding

3 references

17 October 2017

Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Structural insight into the mechanisms of enveloped virus tethering by tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Tetherin inhibits HIV-1 release by directly tethering virions to cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

multivesicular body

1 reference

17 October 2017

Rab7A is required for efficient production of infectious HIV-1

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

endosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

late endosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

7 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

17 October 2017

Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

integral component of plasma membrane

1 reference

17 October 2017

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

cell surface

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

3 references

17 October 2017

ISS

17 October 2017

Rab7A is required for efficient production of infectious HIV-1

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

membrane raft

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

anchored component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

extracellular exosome

3 references

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

azurophil granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

negative regulation of intracellular transport of viral material

biological process

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

regulation of actin cytoskeleton organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

ISS

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

cell-cell signaling

1 reference

17 October 2017

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

response to virus

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

multicellular organism development

1 reference

17 October 2017

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

negative regulation of viral genome replication

negative regulation of cell migration

1 reference

17 October 2017

BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

humoral immune response

1 reference

17 October 2017

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

defense response to virus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

17 October 2017

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

type I interferon signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

negative regulation of cell growth

1 reference

17 October 2017

BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

negative regulation of plasmacytoid dendritic cell cytokine production

1 reference

17 October 2017

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

17 October 2017

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

cell population proliferation

1 reference

17 October 2017

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

3 references

17 October 2017

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

17 October 2017

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

negative regulation of endopeptidase activity

1 reference

17 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q10589&geneProductId=UniProtKB:Q10589

1 reference

17 October 2017

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016