Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21100520)
Watch
English
Caspase recruitment domain family member 18
mammalian protein found in Homo sapiens
ICEBERG caspase-1 inhibitor
CARD18
caspase recruitment domain-containing protein 18
caspase-1 inhibitor Iceberg
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P57730
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P57730
encoded by
CARD18
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P57730
molecular function
peptidase inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
cysteine-type endopeptidase inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
cysteine-type endopeptidase activity involved in execution phase of apoptosis
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730
determination method
IBA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IPI
retrieved
8 April 2019
stated in
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IPI
caspase binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IPI
CARD domain binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IPI
cysteine-type endopeptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
cell component
cytoplasm
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730
determination method
IBA
protein-containing complex
determination method
IDA
3 references
retrieved
8 April 2019
stated in
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IDA
retrieved
8 April 2019
stated in
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IDA
retrieved
8 April 2019
stated in
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IDA
biological process
negative regulation of peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
regulation of apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
inflammatory response
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
ICEBERG: a novel inhibitor of interleukin-1beta generation
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
NAS
execution phase of apoptosis
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P57730&geneProductId=UniProtKB:P57730
determination method
IBA
negative regulation of protein binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IDA
inhibition of cysteine-type endopeptidase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
GOA
curator
UniProt
UniProt protein ID
P57730
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IDA
proteolysis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P57730
determination method
IEA
Identifiers
RefSeq protein ID
NP_067546
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
59082
UniProt protein ID
P57730
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P57730
Ensembl protein ID
ENSP00000436691
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000436691
ENSP00000437035
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437035
ENSP00000437187
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437187
ENSP00000497940
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000497940
PDB structure ID
1DGN
1 reference
stated in
UniProt
UniProt protein ID
P57730
retrieved
21 March 2016
language of work or name
English
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
