(Q21100882)

English

25-hydroxycholesterol 7alpha-hydroxylase activity

Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.

  • GO:0033783
  • cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
  • CYP7B1 oxysterol 7alpha-hydroxylase activity
  • 25-hydroxycholesterol 7alpha-monooxygenase activity

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