Wikidata

(Q21101022)

English

Dual specificity tyrosine phosphorylation regulated kinase 1A

mammalian protein found in Homo sapiens

  • dual specificity YAK1-related kinase
  • mnb protein kinase homolog hp86
  • dual specificity tyrosine-phosphorylation-regulated kinase 1A
  • HP86
  • serine/threonine-specific protein kinase
  • hMNB
  • MNB/DYRK protein kinase
  • protein kinase minibrain homolog
  • serine/threonine kinase MNB
  • dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • DYRK1A
  • MNBH
In more languages

Statements

molecular function
protein binding
determination method
IPI
8 references
retrieved
8 April 2019
stated in
Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of Ser640 in Muscle Glycogen Synthase by DYRK Family Protein Kinases
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
Serine/Threonine Kinase Mirk/Dyrk1B Is an Inhibitor of Epithelial Cell Migration and Is Negatively Regulated by the Met Adaptor Ran-binding Protein M
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
The protein interaction landscape of the human CMGC kinase group
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
retrieved
8 April 2019
stated in
Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IPI
protein serine/threonine kinase activity
determination method
IEA
IGI
ISS
NAS
TAS
8 references
retrieved
8 April 2019
stated in
Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
TAS
retrieved
8 April 2019
stated in
Roles of tau protein in health and disease
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
ISS
retrieved
8 April 2019
stated in
Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
ISS
retrieved
8 April 2019
stated in
A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IGI
retrieved
8 April 2019
stated in
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IEA
cell component
nucleus
determination method
IDA
IEA
ISS
TAS
7 references
retrieved
8 April 2019
stated in
The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IEA
retrieved
8 April 2019
stated in
Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IDA
retrieved
8 April 2019
stated in
Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling
GOA
curator
UniProt
UniProt protein ID
Q13627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627
determination method
IDA
biological process

Identifiers

Ensembl protein ID
PDB structure ID
 
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