(Q33674369)

28 July 2017

title

Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice (English)

1 reference

Dual specificity tyrosine phosphorylation regulated kinase 1A

28 July 2017

main subject

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Serine and arginine rich splicing factor 2

1 reference

microtubule associated protein tau

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positive regulation of RNA splicing

1 reference

1 reference

1 reference

6

Cheng-Xin Gong

1 reference

28 July 2017

Xiaomin Yin

1

1 reference

28 July 2017

Nana Jin

2

1 reference

28 July 2017

Jianhua Shi

3

1 reference

28 July 2017

Yanchong Zhang

4

1 reference

28 July 2017

Yue Wu

5

1 reference

28 July 2017

Khalid Iqbal

7

1 reference

28 July 2017

Fei Liu

8

1 reference

28 July 2017

language of work or name

English

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publication date

4 April 2017

1 reference

28 July 2017

1 reference

28 July 2017

volume

7

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28 July 2017

issue

1

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28 July 2017

page(s)

619

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

4 April 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.

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Regulation of alternative splicing of tau exon 10.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.

14 July 2018

1 reference

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Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

14 July 2018

1 reference

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The selectivity of protein kinase inhibitors: a further update

14 July 2018

1 reference

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The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Arginine/serine-rich protein interaction domain-dependent modulation of a tau exon 10 splicing enhancer: altered interactions and mechanisms for functionally antagonistic FTDP-17 mutations Delta280K AND N279K

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Mutations causing neurodegenerative tauopathies

14 July 2018

1 reference

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O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

14 July 2018

1 reference

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Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

The specificities of protein kinase inhibitors: an update

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Histopathological criteria for progressive dementia disorders: clinical-pathological correlation and classification by multivariate data analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Alzheimer's disease in Down's syndrome: clinicopathologic studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Developmentally regulated expression of specific tau sequences

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Structure and novel exons of the human tau gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5428843

Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study.

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Isoforms changes of tau protein during development in various species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Uptake and distribution of catechins in fetal organs following in utero exposure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-00682-Y

10.1038/S41598-017-00682-Y

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference