(Q34800508)

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Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Alzheimer's disease

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alternative mRNA splicing, via spliceosome

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based on heuristic

inferred from title

Inge Grundke-Iqbal

5

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Inge Grundke-Iqbal

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Europe PubMed Central

PubMed publication ID

4 August 2017

8

object named as

Cheng-Xin Gong

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Europe PubMed Central

PubMed publication ID

4 August 2017

author name string

Jianhua Shi

1

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Europe PubMed Central

PubMed publication ID

4 August 2017

Wei Qian

2

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Europe PubMed Central

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4 August 2017

Xiaomin Yin

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Khalid Iqbal

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Xiaosong Gu

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Fei Ding

7

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Europe PubMed Central

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4 August 2017

Fei Liu

9

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4 August 2017

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publication date

2 March 2011

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Europe PubMed Central

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4 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

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4 August 2017

286

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Europe PubMed Central

PubMed publication ID

4 August 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

14639-14648

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

In vivo selection of kinase-responsive RNA elements controlling alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tau isoform regulation is region- and cell-specific in mouse brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Differential incorporation of tau isoforms in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Cellular tau pathology and immunohistochemical study of tau isoforms in sporadic tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Human postmortem tissue: what quality markers matter?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Arginine/serine-rich protein interaction domain-dependent modulation of a tau exon 10 splicing enhancer: altered interactions and mechanisms for functionally antagonistic FTDP-17 mutations Delta280K AND N279K

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Mutations causing neurodegenerative tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Regulation of tau isoform expression and dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

A protein interaction domain contacts RNA in the prespliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

A conserved Drosophila transportin-serine/arginine-rich (SR) protein permits nuclear import of Drosophila SR protein splicing factors and their antagonist repressor splicing factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Listening to silence and understanding nonsense: exonic mutations that affect splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Transportin-SR, a nuclear import receptor for SR proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

SR proteins and splicing control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Staging of Alzheimer's disease-related neurofibrillary changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Developmentally regulated expression of specific tau sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

The microtubule binding domain of tau protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Tau protein binds to microtubules through a flexible array of distributed weak sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Structure and novel exons of the human tau gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Localization of the catalytic subunit C gamma of the cAMP-dependent protein kinase gene (PRKACG) to human chromosome region 9q13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

8 July 2018

Hereditary Pick's disease with the G272V tau mutation shows predominant three-repeat tau pathology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Pick's disease associated with the novel Tau gene mutation K369I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Quantitative analysis of tau isoform transcripts in sporadic tauopathies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing tau mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Expression of tau mRNA and soluble tau isoforms in affected and non-affected brain areas in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Assessing RNA quality in postmortem human brain tissue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Pick's disease is associated with mutations in the tau gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077661

26 October 2018

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.204453

21 January 2018

Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.204453

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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