Wikidata

(Q21101094)

English

DNA fragmentation factor subunit beta

mammalian protein found in Homo sapiens

  • DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
  • caspase-activated deoxyribonuclease
  • caspase-activated nuclease
  • caspase-activated DNase
  • DFFB
  • DFF-40
  • CPAN
  • DNA fragmentation factor 40 kDa subunit
  • CAD
In more languages

Statements

molecular function
cell component
nucleus
determination method
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O76075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IEA
retrieved
8 April 2019
stated in
DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution
GOA
curator
UniProt
UniProt protein ID
O76075
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IDA
retrieved
8 April 2019
stated in
Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IDA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IDA
retrieved
8 April 2019
stated in
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76075
determination method
IDA
biological process

Identifiers

 
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