(Q24318010)

English

Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state

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scholarly article

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Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state (English)

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positive regulation of apoptotic DNA fragmentation

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Gene Ontology release 2020-05-02

Gene Ontology ID

negative regulation of apoptotic DNA fragmentation

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Gene Ontology release 2020-05-02

Gene Ontology ID

regulation of apoptotic DNA fragmentation

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

DNA fragmentation factor subunit beta

1 reference

GOA release 2020-03-11

DNA fragmentation factor subunit alpha

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GOA release 2020-03-11

apoptotic DNA fragmentation

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GOA release 2020-03-11

CCCTC-binding factor

1 reference

GOA release 2020-03-11

DNA fragmentation factor, beta subunit

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GOA release 2020-03-11

DNA fragmentation factor, alpha subunit

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GOA release 2020-03-11

5

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author name string

Christian Korn

1

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Sebastian R Scholz

2

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Oleg Gimadutdinow

3

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Rudi Lurz

4

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Gregor Meiss

6

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language of work or name

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publication date

18 February 2005

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Journal of Biological Chemistry

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280

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7

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6005-15

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Apoptotic DNA fragmentation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Degradation of chromosomal DNA during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

DNases and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Specific chaperone-like activity of inhibitor of caspase-activated DNase for caspase-activated DNase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Co-translational folding of caspase-activated DNase with Hsp70, Hsp40, and inhibitor of caspase-activated DNase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Cleavage preferences of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease) on naked DNA and chromatin substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

The effect of ICAD-S on the formation and intracellular distribution of a nucleolytically active caspase-activated DNase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

The insulator binding protein CTCF associates with the nuclear matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Barnase-barstar interaction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Ribonuclease inhibitor as an intracellular sentry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Immunity proteins: enzyme inhibitors that avoid the active site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Structural and mechanistic basis of immunity toward endonuclease colicins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Study of DFF45 in its role of chaperone and inhibitor: two independent inhibitory domains of DFF40 nuclease activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

The crystal structure of the nuclease domain of colicin E7 suggests a mechanism for binding to double-stranded DNA by the H-N-H endonucleases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

21 January 2018

Identification of the nuclear factor HMG2 as an activator for DFF nuclease activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

ICAD/DFF Regulator of Apoptotic Nuclease Is Nuclear

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

Spatial organization of four hnRNP proteins in relation to sites of transcription, to nuclear speckles, and to each other in interphase nuclei and nuclear matrices of HeLa cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential Localization of ICAD-L and ICAD-S in Cells Due to Removal of a C-Terminal NLS from ICAD-L by Alternative Splicing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

The roles of arginine 41 and tyrosine 76 in the coupling of DNA recognition to phosphodiester bond cleavage by DNase I: a study using site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of putative active-site residues in the DNase domain of colicin E9 by random mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA structural variations in the E. coli tyrT promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive nuclear localization and initial cytoplasmic apoptotic activation of endogenous caspase-3 evidenced by confocal microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413035200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M413035200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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