(Q39230298)

10 September 2017

Identification of functionally relevant histidine residues in the apoptotic nuclease CAD. (English)

1 reference

10 September 2017

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G Meiss

1

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10 September 2017

S R Scholz

2

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10 September 2017

C Korn

3

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10 September 2017

O Gimadutdinow

4

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10 September 2017

A Pingoud

5

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10 September 2017

language of work or name

English

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publication date

1 October 2001

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10 September 2017

Nucleic Acids Research

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10 September 2017

29

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10 September 2017

19

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10 September 2017

3901-3909

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Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Conformational flexibility in T4 endonuclease VII revealed by crystallography: implications for substrate binding and cleavage

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Structure of the heterodimeric complex between CAD domains of CAD and ICAD

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Apoptotic DNA fragmentation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

A novel endonuclease mechanism directly visualized for I-PpoI

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

The active site of Serratia endonuclease contains a conserved magnesium-water cluster

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Coulombic effects of remote subsites on the active site of ribonuclease A

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Site-directed mutagenesis of the catalytic residues of bovine pancreatic deoxyribonuclease I.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Analysis of the mechanism of the Serratia nuclease using site-directed mutagenesis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

How to measure and predict the molar absorption coefficient of a protein

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

An improved PCR-mutagenesis strategy for two-site mutagenesis or sequence swapping between related genes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Three-dimensional structure of bovine pancreatic DNase I at 2.5 A resolution

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

The subunit structure and active site sequence of porcine spleen deoxyribonuclease.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Histidine-40 of ribonuclease T1 acts as base catalyst when the true catalytic base, glutamic acid-58, is replaced by alanine

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

Structural and mechanistic basis of immunity toward endonuclease colicins

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60245

2.1 Å structure of Serratia endonuclease suggests a mechanism for binding to double-stranded DNA

21 August 2018

1 reference

12 December 2020

Metal Activation of Enzymes in Nucleic Acid Biochemistry

1 reference

12 December 2020

Identification of the nuclear factor HMG2 as an activator for DFF nuclease activity

1 reference

12 December 2020

Studies on RNase T1 mutants affecting enzyme catalysis

1 reference

12 December 2020

Two histidine residues are essential for ribonuclease T1 activity as is the case for ribonuclease A

1 reference

12 December 2020

Ionic and cofactor requirements for the activity of the apoptotic endonuclease DFF40/CAD

1 reference

12 December 2020

Sau3AI, a monomeric type II restriction endonuclease that dimerizes on the DNA and thereby induces DNA loops

1 reference

12 December 2020

Identification of regulatory and catalytic domains in the apoptosis nuclease DFF40/CAD

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/29.19.3901

1 reference

10 September 2017

1 reference

10 September 2017

PubMed publication ID

11574671

1 reference