(Q35091420)

6 August 2017

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title

Degradation of chromosomal DNA during apoptosis (English)

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6 August 2017

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Nagata S

1

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6 August 2017

Nagase H

2

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6 August 2017

Kawane K

3

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6 August 2017

Mukae N

4

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6 August 2017

Fukuyama H

5

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6 August 2017

1 January 2003

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Cell Death & Differentiation

6 August 2017

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6 August 2017

10

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6 August 2017

1

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6 August 2017

108-116

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401161

6 August 2017

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cites work

Programmed cell death in animal development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

A matter of life and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Corpse clearance defines the meaning of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptosis: cell death defined by caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptosis and programmed cell death in immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification of deoxyribonuclease II as an endonuclease involved in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Purification, characterization, and amino acid sequencing of DNase gamma from rat spleen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Features of systemic lupus erythematosus in Dnase1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Involvement of an ICE-like protease in Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptosis by a cytosolic extract from Fas-activated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Cytosolic nuclease activated by caspase-3 and inhibited by DFF-45

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Molecular cloning and characterization of human caspase-activated DNase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

A novel activation mechanism of caspase-activated DNase from Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Cleavage preferences of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease) on naked DNA and chromatin substrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Co-translational folding of caspase-activated DNase with Hsp70, Hsp40, and inhibitor of caspase-activated DNase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification and developmental expression of inhibitor of caspase-activated DNase (ICAD) in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Characterization of the rat DNA fragmentation factor 35/Inhibitor of caspase-activated DNase (Short form). The endogenous inhibitor of caspase-dependent DNA fragmentation in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Study of DFF45 in its role of chaperone and inhibitor: two independent inhibitory domains of DFF40 nuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Multiple domains of DFF45 bind synergistically to DFF40: roles of caspase cleavage and sequestration of activator domain of DFF40

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Structure of the heterodimeric complex between CAD domains of CAD and ICAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Differential Localization of ICAD-L and ICAD-S in Cells Due to Removal of a C-Terminal NLS from ICAD-L by Alternative Splicing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Caspases: their intracellular localization and translocation during apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

The regulation of DNAse activities in subcellular compartments of activated thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

ICAD/DFF Regulator of Apoptotic Nuclease Is Nuclear

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

A simple and rapid method for detection of apoptosis in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Structure and promoter analysis of murine CAD and ICAD genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Mitochondrial endonuclease G is important for apoptosis in C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Apoptotic nuclear morphological change without DNA fragmentation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Lack of obvious 50 kilobase pair DNA fragments in DNA fragmentation factor 45-deficient thymocytes upon activation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Two distinct pathways leading to nuclear apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Death by a thousand cuts: an ever increasing list of caspase substrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Dna fragmentation factor 45 mutant mice exhibit resistance to kainic acid-induced neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

DNA fragmentation factor 45 deficient mice exhibit enhanced spatial learning and memory compared to wild-type control mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identification of a factor that links apoptotic cells to phagocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Do macrophages kill through apoptosis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Phagocytosis promotes programmed cell death in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Mutually regulated expression of caspase-activated DNase and its inhibitor for apoptotic DNA fragmentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401161

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401161

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference