(Q28567075)

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Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures

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scholarly article

1 reference

31 January 2017

Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

apoptotic process

0 references

cerebral infarction

1 reference

based on heuristic

inferred from title

transient cerebral isolation

1 reference

based on heuristic

inferred from title

author name string

G Cao

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

W Pei

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

J Lan

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

R A Stetler

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

Y Luo

5

1 reference

Europe PubMed Central

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12 May 2020

T Nagayama

6

1 reference

Europe PubMed Central

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12 May 2020

S H Graham

7

1 reference

Europe PubMed Central

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12 May 2020

X M Yin

8

1 reference

Europe PubMed Central

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12 May 2020

R P Simon

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

J Chen

10

1 reference

Europe PubMed Central

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12 May 2020

language of work or name

0 references

publication date

1 July 2001

1 reference

31 January 2017

Journal of Neuroscience

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

21

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

4678-4690

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

13

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

Oxidized LDLs alter the activity of the ubiquitin-proteasome pathway: potential role in oxidized LDL-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global ischemia induces apoptosis-associated genes in hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A caspase inhibitor blocks ischaemia-induced delayed neuronal death in the gerbil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in expression of the DNA repair protein complex DNA-dependent protein kinase after ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of apoptotic DNA degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-Xshort is elevated following severe global ischemia in rat brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: the executioners of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and simple method for the isolation of apoptotic DNA fragments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential Localization of ICAD-L and ICAD-S in Cells Due to Removal of a C-Terminal NLS from ICAD-L by Alternative Splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and characterization of human caspase-activated DNase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death in cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cerebral ischemia activates nuclear factor-kappa B prior to evidence of DNA fragmentation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient global ischemia triggers expression of the DNA damage-inducible gene GADD45 in the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple molecular penumbras after focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization signals (NLS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of the Nedd2 gene encoding an ICE/Ced-3-like cysteine protease in the gerbil brain after transient global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of bax protein levels in neurons following cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The time-course of DNA fragmentation in the choroid plexus and the CA1 region following transient global ischemia in the rat brain. The effect of intra-ischemic hypothermia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and developmental expression of inhibitor of caspase-activated DNase (ICAD) in Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: enemies within

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron microscopic evidence against apoptosis as the mechanism of neuronal death in global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of beta2-adrenoceptors inhibits apoptosis in rat brain after transient forebrain ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the rat DNA fragmentation factor 35/Inhibitor of caspase-activated DNase (Short form). The endogenous inhibitor of caspase-dependent DNA fragmentation in neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of hippocampal neuronal damage after global ischemia by neuronal overexpression of BCL-2 in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic cell death in brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11425895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-13-04678.2001

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762351&resulttype=core&format=json

12 May 2020

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