(Q38323810)

2 September 2017

Changes in expression of the DNA repair protein complex DNA-dependent protein kinase after ischemia and reperfusion (English)

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2 September 2017

D A Shackelford

1

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2 September 2017

T Tobaru

series ordinal

2

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2 September 2017

S Zhang

series ordinal

3

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2 September 2017

J A Zivin

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

1 June 1999

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2 September 2017

Journal of Neuroscience

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2 September 2017

19

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2 September 2017

12

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2 September 2017

4727-4738

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Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat

2 September 2017

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12 December 2020

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

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12 December 2020

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

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12 December 2020

Studies of the influence of biogenic amines on central nervous system ischemia

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12 December 2020

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

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12 December 2020

Non-linear epitopes of the large subunit of Ku autoantigen recognized by monoclonal and autoantibodies

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12 December 2020

The DNA-activated protein kinase -- DNA-PK

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12 December 2020

Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis

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12 December 2020

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions

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12 December 2020

Ku autoantigen is a potential major cause of nonspecific bands in electrophoretic mobility shift assays

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12 December 2020

Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain

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12 December 2020

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

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12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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12 December 2020

CPP32/Yama/apopain cleaves the catalytic component of DNA-dependent protein kinase in the holoenzyme

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12 December 2020

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

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12 December 2020

Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen

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12 December 2020

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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12 December 2020

Spatial resolution of fodrin proteolysis in postischemic brain

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12 December 2020

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

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12 December 2020

Oxidative stress in neurodegenerative diseases

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12 December 2020

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

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12 December 2020

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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12 December 2020

DNA looping by Ku and the DNA-dependent protein kinase

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12 December 2020

The nuclear serine/threonine protein kinase DNA-PK

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12 December 2020

The DNA-dependent protein kinase catalytic subunit (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells

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12 December 2020

Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells

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12 December 2020

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

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12 December 2020

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

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12 December 2020

DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis

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12 December 2020

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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12 December 2020

Cell death suggestive of apoptosis after spinal cord ischemia in rabbits

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12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

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12 December 2020

Identification of nuclear factor IV/Ku autoantigen in a human 2D-gel protein database. Modification of the large subunit depends on cellular proliferation

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12 December 2020

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

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12 December 2020

Endonuclease activation following focal ischemic injury in the rat brain.

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12 December 2020

Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers.

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12 December 2020

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

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12 December 2020

The DNA-dependent protein kinase: a matter of life and (cell) death

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12 December 2020

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

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12 December 2020

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

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12 December 2020

Activation of nuclear factor-kappaB in the rabbit spinal cord following ischemia and reperfusion

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12 December 2020

Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site.

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12 December 2020

Response of postmitotic neurons to X-irradiation: implications for the role of DNA damage in neuronal apoptosis.

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12 December 2020

DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat.

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12 December 2020

Spectrum of neurological deficits in experimental CNS ischemia. A quantitative study.

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12 December 2020

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

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12 December 2020

Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease

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12 December 2020

Role of poly(ADP-ribose) formation in DNA repair

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12 December 2020

Damage, repair, and mutagenesis in nuclear genes after mouse forebrain ischemia-reperfusion

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12 December 2020

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

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12 December 2020

EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA.

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12 December 2020

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen

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12 December 2020

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

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12 December 2020

DNA single-strand breaks in postischemic gerbil brain detected by in situ nick translation procedure

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12 December 2020

Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens

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12 December 2020

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

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12 December 2020

Levels of synthesis of primate-specific nuclear proteins differ between growth-arrested and proliferating cells

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12 December 2020

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

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12 December 2020

Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus

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12 December 2020

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

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12 December 2020

Apoptosis and protein expression after focal cerebral ischemia in rat.

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12 December 2020

Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death.

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12 December 2020

Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo

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12 December 2020

DNA-dependent ATPase from HeLa cells is related to human Ku autoantigen

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12 December 2020

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

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12 December 2020

Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium.

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12 December 2020

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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12 December 2020

Functional interaction between DNA-PK and c-Abl in response to DNA damage

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12 December 2020

Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia

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12 December 2020

DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease

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12 December 2020

Three distinct phases of fodrin proteolysis induced in postischemic hippocampus. Involvement of calpain and unidentified protease

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12 December 2020

Role of oxidants in ischemic brain damage

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12 December 2020

Neuronal Apoptosis and Necrosis Following Spinal Cord Ischemia in the Rat

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12 December 2020

Antigenic determinants of the Ku (p70/p80) autoantigen are poorly conserved between species

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12 December 2020

Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

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12 December 2020

Protein measurement with the Folin phenol reagent

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12 December 2020

p53 expression in brain after middle cerebral artery occlusion in the rat

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12 December 2020

Identifiers

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