(Q21981708)

English

DNA fragmentation factor, alpha subunit

mammalian protein found in Mus musculus

DNA fragmentation factor subunit alpha
inhibitor of CAD
ICAD
DNA fragmentation factor 45 kDa subunit
DFF-45
Dffa

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

DNA fragmentation factor 45kDa, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O54786

DNA fragmentation factor 45

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O54786

DNA fragmentation factor 45kDa, middle domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CIDE-N domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IBA

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54786&geneProductId=UniProtKB:O54786

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IEA

biological process

positive regulation of apoptotic process

1 reference

8 April 2019

Endonuclease G is required for early embryogenesis and normal apoptosis in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IMP

negative regulation of apoptotic DNA fragmentation

4 references

8 April 2019

Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

8 April 2019

Endonuclease G is required for early embryogenesis and normal apoptosis in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

8 April 2019

DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IEA

thymocyte apoptotic process

1 reference

8 April 2019

DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IMP

apoptotic DNA fragmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54786

determination method

IEA

negative regulation of execution phase of apoptosis

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O54786

DNA fragmentation factor 45kDa, middle domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O54786

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

20 March 2016

language of work or name

English

(Q21981708)

DNA fragmentation factor, alpha subunit

Statements

Identifiers

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