(Q21101953)

sequence-specific DNA binding

1 reference

8 April 2019

The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

histone deacetylase binding

1 reference

8 April 2019

The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

4 references

8 April 2019

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

8 April 2019

The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14526&geneProductId=UniProtKB:Q14526

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

multicellular organism development

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

negative regulation of Wnt signaling pathway

1 reference

8 April 2019

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

positive regulation of DNA damage response, signal transduction by p53 class mediator

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

negative regulation of transcription by RNA polymerase II

ISS

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

8 April 2019

The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

Wnt signaling pathway

1 reference

8 April 2019

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14526&geneProductId=UniProtKB:Q14526

regulation of transcription, DNA-templated

1 reference

8 April 2019

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

cellular response to DNA damage stimulus

TAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14526

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14526

Zinc finger C2H2-type

1 reference

stated in

InterPro Release 71.0