Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24337920)
Watch
English
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
title
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
main subject
molecular biology
0 references
HIC ZBTB transcriptional repressor 1
1 reference
stated in
GOA release 2020-03-11
negative regulation of Wnt signaling pathway
1 reference
stated in
GOA release 2020-03-11
C-terminal binding protein 1
1 reference
stated in
GOA release 2020-03-11
Transcription factor 7 like 2, T cell specific, HMG box
1 reference
stated in
GOA release 2020-03-11
Hypermethylated in cancer 1
1 reference
stated in
GOA release 2020-03-11
author
Tomas Valenta
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Bohumil Fafilek
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author name string
Jan Lukas
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Lenka Doubravska
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Vladimir Korinek
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
language of work or name
English
0 references
publication date
25 May 2006
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
volume
25
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
page(s)
2326-2337
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
describes a project that uses
plasmid design
1 reference
based on heuristic
inferred from Methods description
transfection
1 reference
based on heuristic
inferred from Methods description
luciferase assay
1 reference
based on heuristic
inferred from Methods description
Electrophoretic mobility shift assay
1 reference
based on heuristic
inferred from Methods description
immunofluorescence microscopy
1 reference
based on heuristic
inferred from Methods description
RNA purification
1 reference
based on heuristic
inferred from Methods description
real-time polymerase chain reaction
1 reference
based on heuristic
inferred from Methods description
Chromatin immunoprecipitation
1 reference
based on heuristic
inferred from Methods description
cites work
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Nuclear speckles: a model for nuclear organelles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
The Wnt signaling pathway in development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Lissencephaly and other malformations of cortical development: 1995 update
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
19 March 2017
Wnt signalling in stem cells and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
7 April 2017
Gene silencing in cancer in association with promoter hypermethylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
7 April 2017
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
7 April 2017
Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
beta-Catenin regulates the expression of tenascin-C in human colorectal tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
27 September 2017
TCF/LEF factor earn their wings
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
30 May 2018
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
29 November 2018
The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1478201
retrieved
29 November 2018
Identifiers
DOI
10.1038/SJ.EMBOJ.7601147
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PMCID
1478201
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PubMed ID
16724116
1 reference
stated in
Europe PubMed Central
PMCID
1478201
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16724116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
ResearchGate publication ID
7058980
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit