(Q24293496)

negative regulation of canonical Wnt signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Rork Kuick

5

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author name string

Janet Y Leung

1

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Frank T Kolligs

2

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Rong Wu

3

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Yali Zhai

4

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Samir Hanash

6

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Kathleen R Cho

7

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Eric R Fearon

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

14 June 2002

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published in

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volume

277

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page(s)

21657-65

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issue

24

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cites work

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

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Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors

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Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

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Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

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Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A

21 January 2018

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

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Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

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Inhibition of Wnt signaling pathway by a novel axin-binding protein

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Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

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Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M200139200

1 reference

Consolidated OpenCitations Corpus – April 2017

1407554

1407554

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference