(Q28565473)

31 January 2017

title

Inhibition of Wnt signaling pathway by a novel axin-binding protein (English)

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31 January 2017

T. Kadoya

1

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31 January 2017

S. Kishida

2

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31 January 2017

A. Fukui

3

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31 January 2017

T. Hinoi

4

1 reference

31 January 2017

T. Michiue

5

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31 January 2017

M. Asashima

6

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31 January 2017

A. Kikuchi

7

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31 January 2017

language of work or name

English

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publication date

24 November 2000

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

275

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31 January 2017

issue

47

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31 January 2017

page(s)

37030–37037

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Mechanisms of Wnt signaling in development

31 January 2017

cites work

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

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Roles of Axin in the Wnt signalling pathway

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

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Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

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GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

21 January 2018

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

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A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

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DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

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Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

21 January 2018

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Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction

21 January 2018

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Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 January 2018

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Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription

21 January 2018

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Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

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21 January 2018

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Axin directly interacts with plakoglobin and regulates its stability

21 January 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

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Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells

21 January 2018

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Analysis of Dishevelled signalling pathways during Xenopus development.

21 January 2018

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Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cells

21 January 2018

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Regulation of the protein kinase activity of Shaggy(Zeste-white3) by components of the wingless pathway in Drosophila cells and embryos

21 January 2018

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Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

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Casein kinase 2 associates with and phosphorylates dishevelled

21 January 2018

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Casein kinase I transduces Wnt signals

21 January 2018

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Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

21 January 2018

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Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

21 January 2018

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Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005984200

Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005984200

PEST sequences and regulation by proteolysis

21 January 2018

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The effects of a lethal mutation responsible for duplications and twinning in mouse embryos

21 January 2018

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The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005984200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017