(Q48263741)

10 February 2018

title

Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. (English)

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10 February 2018

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10 February 2018

James G. Herman

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object named as

James G Herman

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10 February 2018

Stephen B. Baylin

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object named as

Stephen B Baylin

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10 February 2018

author name string

Wen Yong Chen

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10 February 2018

Xiaobei Zeng

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10 February 2018

Mark G Carter

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10 February 2018

Craig N Morrell

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10 February 2018

Ray-Whay Chiu Yen

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10 February 2018

D Neil Watkins

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10 February 2018

Joseph L Mankowski

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10 February 2018

language of work or name

English

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publication date

21 January 2003

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10 February 2018

published in

Nature Genetics

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10 February 2018

volume

33

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10 February 2018

issue

2

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10 February 2018

page(s)

197-202

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10 February 2018

https://scigraph.springernature.com/pub.10.1038/ng1077

exact match

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cites work

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

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7 January 2021

The POZ domain: a conserved protein-protein interaction motif

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7 January 2021

Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer

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7 January 2021

DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis.

1 reference

7 January 2021

Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.

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7 January 2021

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7 January 2021

Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids

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7 January 2021

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

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7 January 2021

Mouse models of tumor development in neurofibromatosis type 1

1 reference

7 January 2021

Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53

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7 January 2021

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

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7 January 2021

Tumor spectrum analysis in p53-mutant mice

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7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

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7 January 2021

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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7 January 2021

Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promise

1 reference

7 January 2021

Promoter hypermethylation--can this change alone ever designate true tumor suppressor gene function?

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7 January 2021

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

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7 January 2021

A method for isolation and purification of specific antibodies to a protein fused to the GST

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7 January 2021

Identifiers

DOI

10.1038/NG1077

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10 February 2018

Dimensions Publication ID

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10 February 2018