(Q21102036)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P50148

G-protein alpha subunit, group Q

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P50148

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P50148

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

type 2A serotonin receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

GTPase activator activity

1 reference

31 October 2017

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

protein binding

5 references

8 April 2019

Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

A retinoic acid receptor RARα pool present in membrane lipid rafts forms complexes with G protein αQ to activate p38MAPK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

β-Arrestin-1 directly interacts with Gαs and regulates its function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

GTPase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

3 references

31 October 2017

31 October 2017

Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

31 October 2017

guanyl nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

G protein-coupled receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

1 reference

31 October 2017

signal transducer activity

GTPase activity

Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

GTPase activator activity

1 reference

8 April 2019

Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

cell body

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

nuclear membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

3 references

8 April 2019

8 April 2019

Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

Interaction of folate receptor with signaling molecules lyn and G(alpha)(i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

photoreceptor outer segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

lysosomal membrane

1 reference

31 October 2017

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

dendrite

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

extracellular exosome

4 references

31 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

31 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

heterotrimeric G-protein complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

lysosomal membrane

1 reference

8 April 2019

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

extracellular exosome

3 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

G protein-coupled acetylcholine receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

skeletal system development

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

negative regulation of protein kinase activity

1 reference

8 April 2019

Regulation of GSK-3beta and beta-Catenin by Galphaq in HEK293T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

neuron remodeling

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

embryonic digit morphogenesis

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

protein stabilization

1 reference

8 April 2019

Regulation of GSK-3beta and beta-Catenin by Galphaq in HEK293T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

blood coagulation

1 reference

8 April 2019

Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

post-embryonic development

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

regulation of melanocyte differentiation

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

activation of phospholipase C activity

1 reference

8 April 2019

Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

entrainment of circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

platelet activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

forebrain neuron development

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

heart development

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

maternal behavior

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

phototransduction, visible light

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

1 reference

8 April 2019

developmental pigmentation

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50148&geneProductId=UniProtKB:P50148

positive regulation of GTPase activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

action potential

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

adenylate cyclase-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

glutamate receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Regulation of GSK-3beta and beta-Catenin by Galphaq in HEK293T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50148

http://www.uniprot.org/uniprot/P21279.txt?version=168

Identifiers

MeSH descriptor ID

C554061

subject named as

GNAQ protein, human

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 November 2015

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

1 reference

9 November 2015

http://www.uniprot.org/uniprot/P21279.txt?version=168

UMLS CUI

C2975446

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023