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(Q21102480)
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English
Complement C7
mammalian protein found in Homo sapiens
C7
complement component 7
complement component C7
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P10643
part of
Thrombospondin type-1 (TSP1) repeat superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Sushi/SCR/CCP superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Complement component C7
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Sushi/SCR/CCP domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Factor I / membrane attack complex, protein family
1 reference
based on heuristic
inferred from protein domain or family
Membrane attack complex component/perforin (MACPF) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Low-density lipoprotein (LDL) receptor class A, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Thrombospondin type-1 (TSP1) repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
Low-density lipoprotein (LDL) receptor class A repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
Membrane attack complex component/perforin domain, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P10643
encoded by
C7
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P10643
molecular function
growth factor activity
determination method
IEA
1 reference
retrieved
14 March 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P10643
determination method
IEA
cell component
extracellular region
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
extracellular exosome
determination method
IDA
2 references
retrieved
26 September 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P10643&geneProductId=UniProtKB:P10643
determination method
IDA
retrieved
26 September 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P10643&geneProductId=UniProtKB:P10643
determination method
IDA
membrane attack complex
determination method
IDA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
The structure of human complement component C7 and the C5b-7 complex
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
retrieved
8 April 2019
stated in
Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IDA
extracellular exosome
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
HDA
biological process
complement activation
determination method
TAS
1 reference
retrieved
26 September 2017
stated in
The structure of human complement component C7 and the C5b-7 complex
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P10643&geneProductId=UniProtKB:P10643
determination method
TAS
cytolysis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
regulation of complement activation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
TAS
complement activation, alternative pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
complement activation, classical pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
innate immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
cellular sodium ion homeostasis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
complement activation
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
The structure of human complement component C7 and the C5b-7 complex
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10643
determination method
IEA
has part(s)
Thrombospondin type-1 (TSP1) repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Low-density lipoprotein (LDL) receptor class A, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Factor I / membrane attack complex
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
sushi/SCR/CCP domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
low-density lipoprotein (LDL) receptor class A repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Membrane attack complex component/perforin (MACPF) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
Membrane attack complex component/perforin domain, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P10643
different from
C7
0 references
Identifiers
MeSH descriptor ID
D003184
0 references
RefSeq protein ID
NP_000578
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
730
UniProt protein ID
P10643
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P10643
Ensembl protein ID
ENSP00000322061
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000322061
PDB structure ID
2WCY
1 reference
stated in
UniProt
UniProt protein ID
P10643
retrieved
9 August 2016
language of work or name
English
UMLS CUI
C0009524
1 reference
based on heuristic
inferred by common MeSH mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
24 May 2023
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