Wikidata

(Q21105627)

English

DEAD-box helicase 3 X-linked

mammalian protein found in Homo sapiens

  • ATP-dependent RNA helicase DDX3X
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3
  • DEAD box, X isoform
  • helicase-like protein 2
  • DEAD/H box-3
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
  • HLP2
  • DDX3X
  • DEAD box protein 3, X-chromosomal
In more languages

Statements

molecular function
protein binding
determination method
IPI
24 references
retrieved
8 April 2019
stated in
RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.
GOA
curator
UniProt
UniProt protein ID
O00571
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
The DHX33 RNA Helicase Promotes mRNA Translation Initiation
GOA
curator
UniProt
UniProt protein ID
O00571
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus core protein interacts with cellular putative RNA helicase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus core protein interacts with a human DEAD box protein DDX3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus infection protein network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
DEAD-box RNA helicase Belle/DDX3 and the RNA interference pathway promote mitotic chromosome segregation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Viral immune modulators perturb the human molecular network by common and unique strategies
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Human DDX3 interacts with the HIV-1 Tat protein to facilitate viral mRNA translation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus core protein binds to a DEAD box RNA helicase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
retrieved
8 April 2019
stated in
Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571
determination method
IPI
cell component
biological process

Identifiers

Ensembl protein ID
 
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