(Q21105842)

Transcription factor E2F4

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

E2F-DP heterodimerization region

1 reference

E2F/DP family, winged-helix DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

E2F transcription factor, CC-MB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

7 November 2018

E2F transcriptional activation requires TRRAP and GCN5 cofactors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

protein domain specific binding

1 reference

8 April 2019

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

DNA-binding transcription factor activity

IPI

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

7 November 2018

E2F transcriptional activation requires TRRAP and GCN5 cofactors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

DNA-binding transcription activator activity, RNA polymerase II-specific

IDA

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

transcription factor binding

IC

1 reference

27 March 2018

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

8 April 2019

In vivo structure of two divergent promoters at the human PCNA locus. Synthesis of antisense RNA and S phase-dependent binding of E2F complexes in intron 1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

12 references

8 April 2019

E2F transcriptional activation requires TRRAP and GCN5 cofactors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

HCF-1 functions as a coactivator for the zinc finger protein Krox20

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

A High-Density Map for Navigating the Human Polycomb Complexome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

promoter-specific chromatin binding

IPI

1 reference

8 April 2019

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

protein dimerization activity

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

DNA-binding transcription factor activity, RNA polymerase II-specific

ISA

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

sequence-specific DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

DNA-binding transcription activator activity, RNA polymerase II-specific

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

1 January 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

4 references

8 April 2019

E2F transcriptional activation requires TRRAP and GCN5 cofactors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

DNA-binding transcription factor activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

E2F transcriptional activation requires TRRAP and GCN5 cofactors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

transcription regulator complex

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

RNA polymerase II transcription regulator complex

IDA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

3 references

regulation of cell size

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

epithelial cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

cell volume homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

multi-ciliated epithelial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

transcription by RNA polymerase II

ISS

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

regulation of transcription involved in G1/S transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

cell projection organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

animal organ morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

motile cilium assembly

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

transcription, DNA-templated

ISS

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

positive regulation of transcription by RNA polymerase II

TAS

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

27 March 2018

E2F transcriptional activation requires TRRAP and GCN5 cofactors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16254&geneProductId=UniProtKB:Q16254

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

positive regulation of transcription by RNA polymerase II

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

E2F transcriptional activation requires TRRAP and GCN5 cofactors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

regulation of cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16254

E2F transcription factor, CC-MB domain

has part(s)

1 reference

E2F/DP family, winged-helix DNA-binding domain

1 reference

inferred by common MeSH mappings on source and on Wikidata

Identifiers

MeSH descriptor ID

D050704

subject named as

E2F4 Transcription Factor

0 references

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference