(Q21106196)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11279

transporter of unknown biochemical mechanism

1 reference

Transporter Classification Database ID

9.A.16.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

Lysosome-associated membrane glycoprotein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein domain specific binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

virus receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

enzyme binding

IPI

1 reference

9 May 2019

The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

integral component of membrane

IPI

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

multivesicular body

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

phagolysosome membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

late endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

8 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

membrane

Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

26 September 2017

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

synaptic vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

cytolytic granule

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

melanosome

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

integral component of plasma membrane

1 reference

9 May 2019

Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

alveolar lamellar body

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

cell surface

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

soma

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

vacuole

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

dendrite

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

phagocytic vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

perinuclear region of cytoplasm

1 reference

9 May 2019

The Salmonella virulence protein SifA is a G protein antagonist

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

sarcolemma

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

lysosome

Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000

9 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

extracellular exosome

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11279&geneProductId=UniProtKB:P11279

cytoplasmic vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

external side of plasma membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

cytosol

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

cytoplasm

1 reference

9 May 2019

Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

8 April 2019

8 April 2019

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

azurophil granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

autolysosome

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

ficolin-1-rich granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

membrane

Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

9 May 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

integral component of synaptic vesicle membrane

HDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

lysosomal membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

9 May 2019

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

late endosome membrane

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

Golgi to lysosome transport

biological process

1 reference

9 May 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

positive regulation of natural killer cell degranulation

1 reference

9 May 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

regulation of organelle transport along microtubule

1 reference

9 May 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

viral entry into host cell

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

viral process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

establishment of protein localization to organelle

1 reference

8 April 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

positive regulation of natural killer cell mediated cytotoxicity

1 reference

9 May 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

granzyme-mediated apoptotic signaling pathway

1 reference

9 May 2019

LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

autophagic cell death

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11279

1 reference

9 May 2019

establishment of protein localization to organelle

lysosome-associated membrane glycoprotein, conserved site

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11279

Identifiers

MeSH descriptor ID

D052118

subject named as

Lysosomal-Associated Membrane Protein 1

0 references

MeSH tree code

D12.776.395.550.550.500

0 references

D12.776.395.550.625.449

0 references

D12.776.543.550.527.500

0 references

D12.776.543.550.625.449

0 references

D12.776.543.750.705.675.554

0 references

D09.400.430.890.550.500

0 references

D09.400.430.890.625.449

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

Transporter Classification Database ID

9.A.16.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023