(Q21106459)

English

Sorting nexin 3

mammalian protein found in Homo sapiens

sorting nexin 3A
Protein SDP3
SNX3
sorting nexin-3

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

transporter of unknown biochemical mechanism

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

phosphatidylinositol-3-phosphate binding

determination method

1 reference

9 May 2019

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phosphatidylinositol-3,5-bisphosphate binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phosphatidylinositol-4-phosphate binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phosphatidylinositol-5-phosphate binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

protein binding

determination method

5 references

9 May 2019

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

A mechanism for retromer endosomal coat complex assembly with cargo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

SNX12 role in endosome membrane transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phosphatidylinositol binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

protein phosphatase binding

determination method

1 reference

9 May 2019

Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phosphatidylinositol phosphate binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

determination method

1 reference

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

early endosome membrane

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

early phagosome

determination method

1 reference

9 May 2019

SNX3 recruits to phagosomes and negatively regulates phagocytosis in dendritic cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

9 May 2019

SNX12 role in endosome membrane transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

phagocytic vesicle

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

cytoplasmic vesicle

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

clathrin-coated vesicle

determination method

1 reference

9 May 2019

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

extrinsic component of membrane

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60493&geneProductId=UniProtKB:O60493

determination method

extracellular exosome

determination method

1 reference

9 May 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

biological process

protein to membrane docking

determination method

1 reference

9 May 2019

A mechanism for retromer endosomal coat complex assembly with cargo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

negative regulation of viral entry into host cell

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

negative regulation of phagocytosis

determination method

1 reference

9 May 2019

SNX3 recruits to phagosomes and negatively regulates phagocytosis in dendritic cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

response to bacterium

determination method

1 reference

9 May 2019

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

negative regulation of protein catabolic process

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

negative regulation of early endosome to late endosome transport

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

membrane invagination

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

regulation of Wnt signaling pathway

determination method

1 reference

9 May 2019

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

intralumenal vesicle formation

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

negative regulation of protein transport

determination method

1 reference

9 May 2019

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

positive regulation of neuron projection development

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

protein transport

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

Wnt signaling pathway

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

protein deubiquitination

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60493

determination method

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60493&geneProductId=UniProtKB:O60493

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000230085

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000230085

ENSP00000296991

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000296991

ENSP00000357975

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000357975

ENSP00000401779

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401779

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

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Multilingual sites(0 entries)

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