Wikidata

(Q21106706)

English

Transporter 2, ATP binding cassette subfamily B member

mammalian protein found in Homo sapiens

  • peptide transporter PSF2
  • Peptide transporter TAP2
  • PSF-2
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
  • antigen peptide transporter 2
  • really interesting new gene 11 protein
  • peptide supply factor 2
  • TAP2
  • ABC transporter, MHC 2
  • ATP-binding cassette, sub-family B (MDR/TAP), member 3
  • peptide transporter involved in antigen processing 2
  • transporter 2, ABC (ATP binding cassette)
  • ATP-binding cassette sub-family B member 3
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
11 references
retrieved
9 May 2019
stated in
TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide
GOA
curator
UniProt
UniProt protein ID
Q03519
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Structural arrangement of the transmission interface in the antigen ABC transport complex TAP.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
retrieved
9 May 2019
stated in
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519
determination method or standard
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D000071450
subject named as
ATP Binding Cassette Transporter, Subfamily B, Member 3
0 references
Ensembl protein ID
 
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